This family-friendly Disney series follows the Duncan clan of Denver, Colo., as they adjust to the arrival of their newest member, Charlotte "Charlie" Duncan (Mia Talerico). Older sister Teddy (Bridgit Mendler) maintains a video diary offering advice for Charlie as she grows up. Meanwhile, parents Bob (Eric Allan Kramer), an exterminator, and Amy (Leigh Allyn Baker), a nurse, juggle the demands of home and work.